Dr Amitesh Khare started his medical career the way many do – one patient at a time. Working in underserved settings, he saw firsthand how even a simple diagnosis or timely referral could dramatically alter someone’s life. “That’s when it became clear – healthcare is one of the most powerful equalisers,” he says.
But over time, the patterns grew louder than the patients. It was not just about clinical knowledge. It was about systems failing to catch what clinicians already knew. Delays. Inefficiencies. Broken workflows. “What patients needed wasn’t more diagnosis – they needed the system to act faster, smarter, and more human.”
Today, Dr Khare is leading a stealth-mode digital health and AI venture that focuses on the last mile – the messy, often-overlooked space between a well-built tool and its actual use in the real world. “One of the biggest turning points,” he shares, “was watching a highly accurate AI model fail because no one used it. Nurses found the alerts intrusive, doctors ignored them, and there was no clear accountability.”
That experience taught him something crucial: in healthcare, the smartest tech is useless unless it fits into people, processes, and practice.
His current work centers on designing clinical tools that influence action – not just prediction. “We shifted from building models to building nudges – timely prompts that help care teams act before it’s too late,” he says. “It’s not about data. It’s about outcomes.”
At ISB (PGP PRO, Class of 2024), Dr Khare found the strategic lens he needed to scale his thinking. “ISB helped me shift from solving clinical problems in isolation to designing solutions that scale and lead to sustainable patient outcomes.”
Dr Amitesh Khare is an alumnus of the ISB PGP PRO Class of 2024. This story part of the series curated on the occasion of Doctors’ Day 2025.